Clom-Resv-ZMA is a new treatment option for Adult-Onset Hypogonadism
What is Clom-Resv-ZMA?
This formulation designed to improve endogenous testosterone production in patients with adult-onset hypogonadism, secondary hypogonadism.
Clomiphene 12.5mg- works as SERM (Selective Estrogen Receptor Modulator) which in composition is a racemic mixture consisting of zuclomiphene (z-isomer ~38%) and enclomiphene (E-isomer ~62%), each with distinct pharmacologic properties.
Clomiphene acts at the level of the hypothalamus, occupying cell surface and intracellular estrogen receptors (ERs) for longer durations than natural estrogen. This interferes with receptor recycling, effectively depleting hypothalamic ERs and modulating normal estrogenic negative feedback resulting in endogenous testosterone production.
Resveratrol -50mg- Natural Aromatase inhibitor for xenoestrogens but also doesn’t counter the effects of natural endogenous estrogens. This mechanism allows body to conserve the testosterone it has and may facilitate in improving testosterone levels. Maintaining healthy body composition by preventing Leptin release form Adipocytes, increased antioxidant activity by Superoxide Dismutase (SOD) synthesis – anti-aging enzymes and improve endothelial function.
ZMA+B6 210mg – a combination of Zinc, Magnesium and Aspartic acid (D) with Vitamin B6 – have a considerable impact in improving testosterone production by providing nutrients required for androgens including testosterone. One study indicated up to 30% increase in endogenous production when combined with an effective work-put plan to improve lean body mass.